Description
An inhibitor of arginase and p70S6K1; inhibits arginase-mediated urea production in J774A.1 macrophage lysates at 10 mM; inhibits TNF-α-induced p70S6K1 activation in HUVECs at 20 mM; reduces microgliosis and the level of amyloid-β fibrils in the hippocampus, as well as improves learning and memory in the Morris water maze in the 3xTg mouse model of Alzheimer’s disease